This leaflet provides information on treatment with PUVA (Psoralen in a diluted solution and ultraviolet A light) which is used to treat a number of skin conditions. You will have received further information about your specific condition. It covers the actual treatment, the risks involved and advice on what you should and shouldn’t do before and after treatment. If you have any further questions, please ask a member of staff.
What is PUVA?
Ultraviolet radiation from artificial light sources have been used by dermatologists for over 100 years and is widely used and effective for treating a number of skin conditions. Clinical choice of PUVA treatment depends on a wide range of factors including age, disease, skin type, previous therapy andcurrent medication.
P= Psoralen UVA = the wavelength of light therapy. The Psoralen and UVA light are used together and are referred to as PUVA. Immersion prior to treatment with Psoralen will sensitise the immersed skin to UV light allowing lower doses of UVA (longer ultraviolet wavelengths) to be effective in clearing your skin disease. It does not affect your skin elsewhere.
What is the aim of treatment?
The aim of the treatment is to clear your skin, although it will not be effective in everybody. It is difficult to know how long your skin will remain clear for after treatment, but it is likely that you will require further treatment in the future. Your doctor can discuss this with you. Most patients are not routinely followed up after successful treatment, but you can ask your GP to refer you back if you require more treatment
Are there any risks?
The most common side effects of this treatment are erythema/redness/sunburn-like reactions to exposed skin. Redness can take 2-3 days to appear and can last for more than a week. Please inform the phototherapy team nurse prior to your treatment if you experience any side effects
Other potential short term side effects include:
- Dry/ itchy skin.
- Worsening of skin disease.
- Tanning – increased pigmentation to the treated area.
- Blistering.
Longer-term side effects of repeated courses of PUVA include; skin ageing, an increase in freckling and potential skin cancer to treated areas. Skin cancer risk is related to total lifetime exposure to ultraviolet light, as well as other factors such skin type.
There is an increased risk of skin cancer with increasing numbers of courses, and we therefore try to keep courses of treatment as short as possible and widely spaced. The skin on the palms of the hands and soles of the feet are less at risk of this.
Dos and Don’ts
- If you do not wish to wear the hospital gowns, you can bring your own.
- Dry flaky skin will deflect the light, rendering UV therapy ineffective.
- Please moisturise your skin at least 3 times per day.
- You can moisturise your skin up to 2 hours before your exposure to light
- Please avoid using moisturiser and make up that contains SPF unless directed otherwise by the phototherapy team.
- Please use your prescribed steroid ointment/other topical treatment every evening as necessary.
- Avoid fragrances and sunblock before treatment unless you have been told otherwise.
- Always remember to inform the doctor or nurse if you are taking, or about to start any new medications including herbal medications (prescribed or otherwise) or cream while having UV therapy.
- Never use a sunbed and keep sunlight exposure to a minimum during your course of treatment as this may cause erythema (sunburn).
- On bright days, protect treated areas from the sunlight, by wearing long sleeves, a hat etc. Sun block (SPF 30) can be used after treatment or on non-treatment days.
- Jewellery e.g. rings; if worn at the start of treatment should be worn at every treatment thereafter, as areas covered at the start will cause a sunburn reaction if subsequently exposed.
- In order to maximise the benefits of UV, regular and punctual attendance is essential.
Your Treatment
Patients are advised to attend promptly for their scheduled appointment days and times. Please do not turn up outside of your scheduled appointment days/times without discussing first with the phototherapy nurses.
The unit is open Monday to Friday between 7.30am and 4.45pm. Following your consultation with the doctor in the phototherapy clinic, your named nurse will discuss your appointment and treatment procedure with you.
On treatment days only:
- Inform the receptionist of your arrival.
- You will be provided with clear protective glasses to protect your eyes from splashes.
- Your hands/ feet will be soaked for 15 minutes in a diluted psoralen solution, gently agitate the water.
- Only areas that are to be treated should be submerged.
- After this time you will wait for 30 minutes before being exposed to UVA light.
- Wear appropriate clothing- long trousers and a long sleeved top will protect your arms and legs from ultraviolet light exposure whilst travelling to and from the department and during your treatment course.
- You will be given a protective face visor to wear during treatment.
- Tubigrip must be worn to protect unaffected areas at all times (we will supply this).
- You will have treatment on a special unit which is given in J/cm2 we aim to give incremental increases throughout your treatment.
- You must apply sunblock to the submerged/treated areas after your treatment.
- Treatment is given either twice a week on a Monday and Thursday or Tuesday and Friday. Appointments are given on a block booking basis.
- A course of treatment will last up to 12 weeks (24 sessions).
- You must not have PUVA treatment if you are pregnant or breastfeeding
- You should avoid getting pregnant during the treatment course.
Ideally you will develop mild skin redness/pinkness with no discomfort after each treatment. You must inform the phototherapy nurse prior to your treatment if your skin becomes sore or uncomfortable.
Treatment is given either twice a week on a Monday and Thursday or Tuesday and Friday. Appointments are given on a block booking basis.
For further information
Please be advised that you will be discharged if you miss 3 appointments without notifying our department. In case of any queries please contact the Phototherapy department via email on [email protected] or by telephone on 0191 282 0871 or 0191 282 0872 between the hours of 7.30am – 4.45pm. For urgent advice about this treatment out of hours please ring Ward 5 on 0191 282 5599.
Useful websites:
If you would like further information about skin conditions and treatment options, you may wish to have a look at:
www.bad.org.uk/site/1223/Default.aspx
www.dermnetnz.org/procedures/narrowband-uvb.html
www.psoriasis.org/phototherapy
If you have any concerns during your treatment please discuss this with the Phototherapy team. The Patient Advice and Liaison Service (PALS) can offer on-the-spot advice and information about the NHS. You can contact them on Freephone 0800 032 02 02 or e-mail [email protected]